Anti-inflammatory, remorin-like protein from green marine Macroalga Caulerpa sertularioides (S.G.Gmel.) M.Howe

The most prevalent natural source of hydrocolloids, cosmetics, medications, and nutraceuticals is marine seaweed (macroalgae). Numerous bioactivities, including antiviral, anticancer, anti-inflammatory, immunomodulatory characteristics, have been found in bioactive substances such as polyphenols sulfated non-sulfated polysaccharides. As a result, new start-up projects industries based on are emerging all regions the world with abundant biodiversity. In this current investigation, anti-inflammatory activity two different macroalgae Caulerpa racemosa (CR) sertularioides (CS) was evaluated. Consequently, CS demonstrated more antioxidant effects at lower dose than CR. IC50 value for DPPH inhibition 456.1 μg/mL, 180.9 μg/mL CR respectively. A similar result obtained case protein denaturation (PD), membrane stabilization (MS), protease (PI) assays 127.2 135.5 71.88 CR, 66.78 88.96 59.54 Based SDS-PAGE, molecular weight lectin responsible determined 17 kDa. Protein mass fingerprinting performed particular by in-gel trypsin digestion, MALDI-MS analysis, Mascot peptide fingerprinting. Because this, unidentified discovered to be remorin-like that shared 65% its sequence Aegilops tauschii subsp. tauschii. Therefore, it hitherto report presence from green macroalga sertularioides.